Autophagy and Apoptosis

Autophagy and apoptosis are key biochemical mechanisms that keep organismal and cellular homeostasis in check. Supernumerary, damaged, or old cells and organelles are destroyed through apoptosis and autophagy, two self-destructive processes. Autophagy is the cell's natural, conserved breakdown process, which removes unwanted or dysfunctional components via a lysosome-dependent, controlled mechanism. It enables the breakdown and recycling of cellular components in a controlled manner. Autophagy preserves cellular homeostasis by recycling selected intracellular organelles and chemicals, whereas apoptosis fulfils its job by destroying damaged or undesired cells. Autophagy, on the other hand, can cause cell death under specific circumstances. The same stressors can trigger apoptosis and autophagy. The process of programmed cell death is known as apoptosis. It is employed to destroy undesirable cells during early development, such as those between the fingers of a developing hand. Apoptosis is a process that allows the body to rid itself of cells that have been damaged beyond repair in adults. Apoptosis can also help to prevent cancer.

  • Apoptosis
  • Autophagy and its Forms
  • Necroptosis
  • Ferroptosis
  • Cellular and Molecular Mechanism of Autophagy and Apoptosis
  • Link between Autophagy and Apoptosis
  • Cancer and Apoptosis